Daim Ntawv Thov ntawm Laser Micromachining Technology hauv Khoom Siv Khoom Siv Hluav Taws Xob
Thov Ib Leeg
Taw qhia:Laser micromachining keeb kwm nyob hauv cov txheej txheem ntim khoom lag luam semiconductor. Nws ua cov khoom los ntawm ultra-luv pulse laser txiav, drilling, vuam, thiab lwm yam, thiab tom qab ntawd tau txais micro-nanoscale ob-txheej (2D) lossis peb-txheej (3D) cov txheej txheem.
Piv nrog rau cov lasers ntev ntev, ultrashort pulsed laser micromachining yog cov kab tsis sib xws, cov txheej txheem tsis sib txig sib luag nrog kev cuam tshuam loj, qhov tsawg tshaj plaws tshav kub cuam tshuam cheeb tsam thiab siab tswj tau. Nyob rau hauv xyoo tsis ntev los, ultrashort mem tes lasers tau lug siv nyob rau hauv micro-nano fabrication teb xws li microfluidic pab kiag li lawm, microsensors, thiab biomedical daim ntaub ntawv. Tshwj xeeb hauv kev siv tshuaj biomedicine, lasers tuaj yeem paub cov khoom siv nyuaj thiab cov khoom ua tau zoo - thiab kev ua tiav, uas tuaj yeem ua tau raws li cov cai ntawm qee yam tshwj xeeb ntawm cov khoom siv biomedical.
Piv rau cov txheej txheem ua cov tsoos, ultrashort-mem tes laser micromachining muaj qhov zoo ntawm" txias" cov zauv, tsis tshua muaj zog noj, me me kev puas tsuaj, siab neeg, thiab nruj kev ntseeg nyob rau hauv 3D qhov chaw, thiab muaj ib tug heev zoo daim ntawv thov prospect nyob rau hauv lub ua kev kho mob kiag li lawm.
Kev ua lag luam me me ntawm cov khoom siv roj ntsha
Cov yam ntxwv saum npoo ntawm biomaterials tuaj yeem cuam tshuam loj heev ntawm cov cwj pwm ntawm cov hlwb xws li adhesion, nthuav, nthuav dav, thiab sib txawv, thiab yog qhov tseem ceeb cuam tshuam rau biocompatibility ntawm cov ntaub ntawv. Txawm hais tias qhov kev hloov kho saum npoo ntawm cov khoom siv yooj yim tuaj yeem ua rau kom qhov hnyav ntawm cov khoom siv bioactive, muaj teeb meem xws li cov txheej txheem nyuaj, kev tawg sai ntawm cov txheej hauv lub cev, thiab tawg ntawm txheej. Laser micromachining thev naus laus zis hloov pauv cov yam ntxwv saum npoo av los ntawm kev ua ntau yam microstructures nyob rau sab nraud ntawm cov khoom, thiab ua kom zoo dua rau kev ua kom lub ntsej muag sib txawv thiab sib txawv ntawm cov hlwb los ntawm kev hloov micron roughness thiab tom qab qhov sib txawv, thiab yog li muaj lub luag haujlwm tseem ceeb hauv kev hloov pauv kev txheeb raws roj ntsha ntawm cov ntaub so ntswg. nyhuv. Piv nrog rau lwm cov txheej txheem ntawm kev hloov kho saum npoo, txheej txheej txheej txheej saum npoo ntawm cov khoom siv hloov pauv hloov los ntawm lub tshuab thev naus laus zis micromachining tshuab yog nyias, muaj kev cuam tshuam me me ntawm qhov loj, thiab kov yeej qhov tsis txaus ntawm cov qauv kev hloov kho uas twb muaj lawm.
Koufaki li al. siv ib tug femtosecond laser PP ua ib tug tapered nto microstructure nrog ib tug roughness piv ntawm 2.0 rau 5.9 rau ib tug hluas siv lead ua pob zeb ntais nto. Lub microstructure tau theej rau polydimethylsiloxane (PDMS) thiab polyemulsion los ntawm kev hloov chaw. - Polyglycolic acid (PLGA) thiab ORMOCER khoom nto, raws li qhia hauv qab no.
(Daim duab (a) Microstructures npaj nyob rau saum npoo ntawm ib leeg siv lead ua Si, PDMS, PLGA thiab ORMOCER siv laser thev naus laus zis; (b) Kev kho mob ntawm NIH / 3T3 nyob ua neej (ntsuab) thiab cov qe tuag (daj-liab) nyob rau saum npoo ntawm PDMS thiab PLGA lug Micrograph; (c) fluorescence micrographs ntawm nyob hlwb (ntsuab) thiab tuag hlwb (daj-liab) ntawm PC12 rau ntawm qhov chaw ntawm PDMS thiab PLGA lug)
Hauv thaj teb ntawm kev tsim ntaub so ntswg, kawm txog cov yam ntxwv ntawm roj ntsha ntawm lub cev nyob rau saum npoo ntawm cov khoom siv roj ntsha yog qhov tseem ceeb. Kev txhim kho thiab txhim kho ntawm cov khoom muaj sia ntawm cov khoom siv roj ntsha yog lwm txoj kev tsom rau kev txhim kho cov khoom siv biomedical niaj hnub. Nrog cov kev nkag siab tas li ntawm qhov tsis muaj qhov cuam tshuam ntawm biomaterial deg cuam tshuam, ntau thiab ntau cov kws tshawb nrhiav tau paub tias tsuas yog kev tswj tau ncaj qha ntawm biomaterial deg-kev ua haujlwm zoo ntawm cov microscopic yog qhov siv. Tus yuam sij rau kev daws teeb meem ntawm biocompatibility ntawm biomaterials.
Laser micromachining thev naus laus zis tuaj yeem tsim ntau yam qauv txheej txheem nyob rau saum npoo ntawm cov khoom siv roj ntsha, xws li cov ntshiab nanostructures, ntau cov nplai ntawm nanometer, micron cov khoom sib txuas ua ke, thiab tuaj yeem tsim cov txheej txheem tshwj xeeb, cov txheej txheem saum npoo los ntawm ntxiv cov txheej txheem laser micromachining. tsos. Cov kab mob ntawm tes thiab kev sib txawv tuaj yeem kho qhov zoo los ntawm kev sib txawv micron roughness, tom qab yov, thiab lwm yam microstructure loj tsis dhau. Txawm li cas los xij, cov nyhuv ntawm nplaim morphology pauv ntawm cov hlwb yog qhov nyuaj, thiab nws cov haujlwm ntawm kev ua tseem tau tshawb nrhiav. Tam sim no, feem ntau ntawm cov kev tshawb fawb yog tseem nyob rau hauv lub laboratory theem. Cov nyhuv ntawm laser micromachining rau kev hloov kho saum npoo ntawm cov khoom siv roj ntsha tseem yuav tsum muaj ntau hauv vitro thiab hauv vivo Cov kev sim tau tshawb xyuas qhov tseeb.